Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 11/20 | 0.74 |
| ▸ | ADRA1B | P35368 | 10/20 | 0.74 |
| ▸ | ADRA1D | P25100 | 9/20 | 0.74 |
| ▸ | HTR1A | P08908 | 6/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7050369 | 0.95 | HTR1A (0.72) | ADRA1AADRA1BADRA1DHTR1ALMNA | |
| SCHEMBL7678716 | 0.94 | HTR1A (0.81) | ADRA1AADRA1BADRA1DHTR1ALMNA | |
| SCHEMBL8876489 | 0.91 | HTR1A (0.86) | ADRA1AADRA1BADRA1DHTR1ALMNA | |
| SCHEMBL7047929 | 0.90 | HTR1A (0.74) | ADRA1AADRA1BADRA1DHTR1ALMNA | |
| SCHEMBL7054044 | 0.89 | HTR1A (0.69) | ADRA1AADRA1BADRA1DHTR1ALMNA | |
| SCHEMBL7051595 | 0.89 | ADRA1A (0.57) | ADRA1AADRA1BADRA1DHTR1A | |
| SCHEMBL8875596 | 0.87 | HTR1A (0.86) | ADRA1AADRA1BADRA1DHTR1ALMNA | |
| SCHEMBL7689629 | 0.87 | HTR1A (0.76) | ADRA1AADRA1BADRA1DHTR1ALMNA | |
| SCHEMBL7047569 | 0.87 | HTR1A (0.83) | ADRA1AADRA1BADRA1DHTR1ALMNA | |
| Upidosin SCHEMBL6638869 | 0.85 | HTR1A (1.00) | ADRA1AADRA1BADRA1DHTR1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403594-B1 | UROGENTIAL INFECTIONS, ETC | RECORDATI, S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2002-06-11 | — | — | US | claimed |