Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27538168 | 0.83 | — | — | |
| SCHEMBL7689245 | 0.81 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1ALPLALDH1A1SMN1; SMN2 | |
| SCHEMBL7685216 | 0.81 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1ALPLALDH1A1POLB | |
| SCHEMBL7683315 | 0.78 | ALPL (0.60) | HSP90AA1HSP90AB1ALPLALDH1A1POLB | |
| SCHEMBL7680990 | 0.77 | HSP90AA1 (0.35) | HSP90AA1HSP90AB1 | |
| SCHEMBL7680967 | 0.77 | HSP90AA1 (0.35) | HSP90AA1HSP90AB1 | |
| SCHEMBL7690438 | 0.76 | ADORA2A (0.50) | POLBSMN1; SMN2 | |
| SCHEMBL27549231 | 0.75 | ALDH1A1 (0.32) | ALDH1A1POLBSMN1; SMN2HCAR2 | |
| SCHEMBL7688003 | 0.75 | HSP90AA1 (0.35) | HSP90AA1HSP90AB1 | |
| SCHEMBL7687918 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350749-B1 | SODIUM CHANNEL MODULATORS, ANTIARRHYTHMIA AND HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS, ANGINA PECTORIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-1057812-A1 | AMINOGUANIDINE HYDRAZONE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |