Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 8/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683286 | 0.91 | DHODH (0.49) | MAPTKMT2AMEN1LMNASIRT1 | |
| SCHEMBL7679575 | 0.89 | MAPT (0.46) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL7693228 | 0.88 | MEN1 (0.48) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL7681633 | 0.88 | MEN1 (0.48) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL7853413 | 0.88 | MAPT (0.55) | MAPTRAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL7676864 | 0.87 | MEN1 (0.46) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL7676618 | 0.87 | KMT2A (0.46) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL7680379 | 0.86 | MAPT (0.51) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL7683312 | 0.86 | MEN1 (0.46) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL7677831 | 0.86 | MEN1 (0.46) | MAPTKMT2AMEN1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350757-B1 | Beta-carboline compounds | LES LABORATOIRES SERVIER (FR) | 2002-02-26 | — | — | US | disclosed |