Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 11/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693228 | 0.92 | MEN1 (0.48) | DHODHMAPTMEN1KMT2ALMNA | |
| SCHEMBL7684013 | 0.91 | MAPT (0.51) | DHODHMAPTMEN1KMT2ALMNA | |
| SCHEMBL7677069 | 0.88 | MEN1 (0.49) | MAPTMEN1KMT2ALMNAKIF11 | |
| SCHEMBL7851002 | 0.88 | DHODH (0.54) | DHODHMAPTKIF11SIRT1NPSR1 | |
| SCHEMBL7676864 | 0.87 | MEN1 (0.46) | MAPTMEN1KMT2ALMNAKIF11 | |
| SCHEMBL7676618 | 0.87 | KMT2A (0.46) | MAPTMEN1KMT2ALMNAKIF11 | |
| SCHEMBL7681633 | 0.87 | MEN1 (0.48) | MAPTMEN1KMT2ALMNAKIF11 | |
| SCHEMBL7680379 | 0.86 | MAPT (0.51) | MAPTMEN1KMT2ALMNAKIF11 | |
| SCHEMBL7679575 | 0.86 | MAPT (0.46) | MAPTMEN1KMT2ALMNAKIF11 | |
| SCHEMBL7683791 | 0.85 | SIRT1 (0.56) | MAPTMEN1KMT2ALMNAKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350757-B1 | Beta-carboline compounds | LES LABORATOIRES SERVIER (FR) | 2002-02-26 | — | — | US | disclosed |