SCHEMBL7684040

SCHEMBL7684040

N#Cc1ccc(-c2ccc3c(c2)C2(CCCCC2)C(=NOCc2ccccc2)N3)[nH]1

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PGR P06401 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6013825 0.82 PGR (0.46) PGR
SCHEMBL6013853 0.82 PGR (0.46) PGR
SCHEMBL3422468 0.81 PGR (0.70) PGR
SCHEMBL4534292 0.81 PGR (0.70) PGR
SCHEMBL6013814 0.80 PGR (0.55) PGR
SCHEMBL6013851 0.78 PGR (0.46) PGR
SCHEMBL6013826 0.78 PGR (0.37) PGR
SCHEMBL6013828 0.78 PGR (0.37) PGR
SCHEMBL6013864 0.77 PGR (0.46) PGR
SCHEMBL6013862 0.77 PGR (0.46) PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1181275-A1 THIO-OXINDOLE DERIVATIVES American Home Products Corporation (US) 2002-02-27 EP disclosed
WO-2000066555-A1 THIO-OXINDOLE DERIVATIVES AMERICAN HOME PRODUCTS CORPORATION (US) 2000-11-09 WO disclosed