Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 19/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6013825 | 1.00 | PGR (0.46) | PGRPDE7ANR3C1 | |
| SCHEMBL6013814 | 0.92 | PGR (0.55) | PGRPDE7ANR3C1 | |
| SCHEMBL6013862 | 0.84 | PGR (0.46) | PGR | |
| SCHEMBL6013864 | 0.84 | PGR (0.46) | PGR | |
| SCHEMBL6013826 | 0.82 | PGR (0.37) | PGR | |
| SCHEMBL6013828 | 0.82 | PGR (0.37) | PGR | |
| SCHEMBL7684040 | 0.82 | PGR (0.59) | PGR | |
| SCHEMBL6013833 | 0.81 | PGR (0.61) | PGR | |
| SCHEMBL4093722 | 0.77 | PGR (0.53) | PGRNR3C1 | |
| SCHEMBL4093720 | 0.77 | PGR (0.53) | PGRNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091234-B2 | Thio-oxindole derivatives | WYETH (US) | 2006-08-15 | — | — | US | disclosed |
| US-20050054711-A1 | Thio-oxindole derivatives | WYETH | 2005-03-10 | — | — | US | disclosed |
| US-6841568-B2 | Thio-oxindole derivatives | WYETH (US) | 2005-01-11 | — | — | US | disclosed |
| US-20030225109-A1 | Thio-oxindole derivatives | WYETH (US) | 2003-12-04 | — | — | US | disclosed |
| US-6583145-B1 | Thio-oxindole derivatives | WYETH | 2003-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225109-A1 | Thio-oxindole derivatives | PGR, OXTR, PGRMC1 | PGR 1/4885PDE7A 3161/4885NR3C1 12/4885 |
| US-20050054711-A1 | Thio-oxindole derivatives | PGR, OXTR, PGRMC1 | PGR 1/4885PDE7A 3063/4885NR3C1 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.