Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PTGES | O14684 | 3/20 | 0.46 |
| ▸ | TERT | O14746 | 5/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9114209 | 0.84 | MAOB (0.56) | PTGESATMTDP1MAOAMAOB | |
| SCHEMBL1578696 | 0.81 | ATM (0.56) | ALDH1A1PTGESATMTDP1MAOA | |
| SCHEMBL30792379 | 0.80 | MAOB (0.51) | NPC1RAB9AALDH1A1PTGESATM | |
| SCHEMBL7900848 | 0.80 | RAB9A (0.51) | NPC1RAB9AALDH1A1PTGESATM | |
| SCHEMBL572373 | 0.79 | PTGES (0.55) | NPC1RAB9APTGESATMTDP1 | |
| SCHEMBL519418 | 0.79 | PTGES (0.61) | NPC1RAB9APTGESATMTDP1 | |
| SCHEMBL29463874 | 0.79 | PTGES (0.61) | NPC1RAB9APTGESATMTDP1 | |
| SCHEMBL11238714 | 0.79 | MAPT (0.58) | NPC1RAB9AALDH1A1TERTMAOB | |
| SCHEMBL4341126 | 0.78 | PTGES (0.61) | PTGESMAOAMAOB | |
| SCHEMBL7677809 | 0.78 | NPC1 (0.48) | NPC1RAB9AALDH1A1TERTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448203-B1 | CROP PROTECTION AGENTS, IN PARTICULAR AS HERBICIDES AND INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-10 | — | — | US | disclosed |
| CN-1289330-A | Substituted heteroarylmethyl compounds used as herbicides | BAYER AG (DE) | 2001-03-28 | — | — | CN | disclosed |
| EP-1051414-A1 | SUBSTITUTED HETEROARYLMETHYL COMPOUNDS USED AS HERBICIDES | Bayer Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | disclosed |
| CN-1259943-A | Substituted aryluracils | BAYER AG (DE) | 2000-07-12 | — | — | CN | disclosed |
| EP-0973765-A1 | SUBSTITUTED ARYLURACILS | BAYER AG (DE) | 2000-01-26 | — | — | EP | disclosed |
| WO-1999038861-A1 | SUBSTITUTED HETEROARYLMETHYL COMPOUNDS USED AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-08-05 | — | — | WO | disclosed |
| WO-1999001440-A1 | SUBSTITUTED ARYLURACIL HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-14 | — | — | WO | disclosed |
| WO-1998046592-A1 | SUBSTITUTED ARYLURACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-22 | — | — | WO | disclosed |