Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | TERT | O14746 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677446 | 0.89 | HDAC1 (0.40) | HDAC1HDAC6HDAC5CHRM5TERT | |
| SCHEMBL7613555 | 0.87 | CHRM5 (0.37) | HDAC1HDAC6HDAC5CHRM5TERT | |
| SCHEMBL8137593 | 0.81 | CHRM5 (0.41) | HDAC1HDAC6HDAC5CHRM5TERT | |
| SCHEMBL7611954 | 0.80 | CHRM5 (0.39) | HDAC1HDAC6HDAC5CHRM5TERT | |
| SCHEMBL7677845 | 0.80 | BCAT1 (0.46) | HDAC1HDAC6HDAC5CHRM5TERT | |
| SCHEMBL9114664 | 0.77 | MAOB (0.47) | MAOAMAOBAR | |
| SCHEMBL7618281 | 0.76 | CHRM5 (0.37) | HDAC1HDAC6HDAC5CHRM5TERT | |
| SCHEMBL7236458 | 0.75 | MAOB (0.38) | MAOAMAOBHRH3PTGDR2 | |
| SCHEMBL9522971 | 0.74 | SLC22A12 (0.34) | HDAC1HDAC6KMT2A | |
| SCHEMBL8144270 | 0.73 | ALDH1A1 (0.40) | HDAC1HDAC6HDAC5CHRM5TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448203-B1 | CROP PROTECTION AGENTS, IN PARTICULAR AS HERBICIDES AND INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-10 | — | — | US | disclosed |