Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27799176 | 0.87 | ALDH1A1 (0.45) | ALDH1A1LMNAHPGDTSHRCTSD | |
| SCHEMBL5694901 | 0.86 | ALDH1A1 (0.42) | ALDH1A1LMNAHPGDTSHRCTSD | |
| SCHEMBL27761127 | 0.85 | HPGD (0.46) | ALDH1A1LMNAHPGDTSHRCTSD | |
| SCHEMBL27587079 | 0.83 | ALDH1A1 (0.41) | ALDH1A1LMNAHPGDTSHRCTSD | |
| SCHEMBL28139529 | 0.83 | ALDH1A1 (0.41) | ALDH1A1LMNAHPGDTSHRCTSD | |
| SCHEMBL7487933 | 0.83 | ALDH1A1 (0.46) | ALDH1A1LMNAHPGDTSHRCTSD | |
| SCHEMBL30463198 | 0.83 | ALDH1A1 (0.46) | ALDH1A1LMNAHPGDTSHRCTSD | |
| SCHEMBL27782862 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LMNAHPGDTSHRCTSD | |
| SCHEMBL27761126 | 0.81 | ALDH1A1 (0.39) | ALDH1A1LMNAHPGDTSHRCTSD | |
| SCHEMBL28164002 | 0.81 | ALDH1A1 (0.45) | ALDH1A1LMNAHPGDTSHRCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106674079-A | Synthesis method of panobinostat | 南京卡文迪许生物工程技术有限公司 | 2017-05-17 | — | — | CN | claimed |
| EP-0348766-B1 | ALPHA-ARYLACRYLIC-ACID ESTERS AND FUNGICIDES CONTAINING SAME | BASF Aktiengesellschaft (DE) | 1991-04-17 | — | — | EP | claimed |
| CN-110551067-B | Multi-target tacrine derivative and preparation method and application thereof | 山东大学 | 2020-09-08 | — | — | CN | disclosed |
| CN-110551067-A | Multi-target tacrine derivative and preparation method and application thereof | UNIV SHANDONG | 2019-12-10 | — | — | CN | disclosed |
| CN-109627211-A | The method that one kettle way prepares ZEN 90160 | 合肥利夫生物科技有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-107011238-A | Class I histone deacetylase inhibitor and its production and use | 北京化工大学 | 2017-08-04 | — | — | CN | disclosed |
| CN-106674079-A | Synthesis method of panobinostat | 南京卡文迪许生物工程技术有限公司 | 2017-05-17 | — | — | CN | disclosed |
| US-6407100-B1 | HORTICULTURE, AGRICULTURE, WOOD PRESERVATION | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-18 | — | — | US | disclosed |
| US-6355634-B1 | OXIME DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-12 | — | — | US | disclosed |
| EP-0893434-A1 | Intermediates for the preparation of oximethers | Novartis AG (CH) | 1999-01-27 | — | — | EP | disclosed |
| EP-0703215-A1 | Aromatic compounds | CIBA-GEIGY AG (CH) | 1996-03-27 | — | — | EP | disclosed |
| EP-0460575-A1 | Aromatic compounds | CIBA-GEIGY AG (CH) | 1991-12-11 | — | — | EP | disclosed |
| US-5041618-A | α-arylacrylates and fungicides containing these compounds | BASF AKTIENGESELLSCHAFT (DE) | 1991-08-20 | — | — | US | disclosed |
| EP-0348766-B1 | ALPHA-ARYLACRYLIC-ACID ESTERS AND FUNGICIDES CONTAINING SAME | BASF Aktiengesellschaft (DE) | 1991-04-17 | — | — | EP | disclosed |
| EP-0348766-A2 | Alpha-arylacrylic-acid esters and fungicides containing same | BASF Aktiengesellschaft (DE) | 1990-01-03 | — | — | EP | disclosed |