Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5694901 | 0.86 | ALDH1A1 (0.42) | ALDH1A1LMNAHPGDTSHRCTSD | |
| SCHEMBL27761127 | 0.85 | HPGD (0.46) | ALDH1A1LMNAHPGDTSHRCTSD | |
| SCHEMBL27897121 | 0.84 | TSHR (0.38) | ALDH1A1LMNAHPGDTSHRHSD17B10 | |
| SCHEMBL28637275 | 0.84 | TSHR (0.47) | ALDH1A1LMNAHPGDTSHRHSD17B10 | |
| SCHEMBL27587079 | 0.83 | ALDH1A1 (0.41) | ALDH1A1LMNAHPGDTSHRCTSD | |
| SCHEMBL7684247 | 0.83 | ALDH1A1 (0.44) | ALDH1A1LMNAHPGDTSHRCTSD | |
| SCHEMBL3306441 | 0.83 | ALDH1A1 (0.42) | ALDH1A1LMNAHPGDTSHRCTSD | |
| SCHEMBL28291342 | 0.83 | KCNA5 (0.34) | ALDH1A1LMNATSHRHIF1AKMT2A | |
| SCHEMBL27782862 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LMNAHPGDTSHRCTSD | |
| SCHEMBL27761126 | 0.81 | ALDH1A1 (0.39) | ALDH1A1LMNAHPGDTSHRCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106674079-A | Synthesis method of panobinostat | 南京卡文迪许生物工程技术有限公司 | 2017-05-17 | — | — | CN | claimed |
| CN-106674079-A | Synthesis method of panobinostat | 南京卡文迪许生物工程技术有限公司 | 2017-05-17 | — | — | CN | disclosed |