Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 16/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.41 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690125 | 0.83 | PGR (0.54) | PGRNR3C1AR | |
| SCHEMBL7646011 | 0.81 | PGR (0.54) | PGRNR3C1NR3C2AR | |
| SCHEMBL7484171 | 0.75 | PGR (0.55) | PGRNR3C1NR3C2AR | |
| SCHEMBL7646020 | 0.74 | PGR (0.55) | PGRNR3C1NR3C2AR | |
| SCHEMBL4101396 | 0.72 | PGR (1.00) | PGRNR3C1NR3C2AR | |
| SCHEMBL5227050 | 0.72 | PGR (0.76) | PGRNR3C1NR3C2AR | |
| SCHEMBL5228182 | 0.70 | PGR (0.74) | PGRNR3C1NR3C2AR | |
| SCHEMBL4098486 | 0.70 | PGR (0.73) | PGRNR3C1NR3C2AR | |
| SCHEMBL4098488 | 0.70 | PGR (0.73) | PGRNR3C1NR3C2AR | |
| SCHEMBL3423573 | 0.69 | PGR (0.72) | PGRNR3C1NR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355648-B1 | COMPOUNDS AS CONTRACEPTIVES AND PROGESTERONE ANTAGONIST | AMERICAN HOME PRODUCTS CORPORATION | 2002-03-12 | — | — | US | disclosed |