Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 17/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.31 |
| ▸ | MELK | Q14680 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684267 | 0.83 | PGR (0.56) | PGRNR3C1AR | |
| SCHEMBL7646011 | 0.83 | PGR (0.54) | PGRNR3C1AR | |
| SCHEMBL6013827 | 0.77 | PGR (0.49) | PGR | |
| SCHEMBL7646020 | 0.75 | PGR (0.55) | PGRNR3C1ARBACE1 | |
| SCHEMBL5226807 | 0.70 | PGR (0.75) | PGR | |
| SCHEMBL4110098 | 0.70 | PGR (1.00) | PGRNR3C1 | |
| SCHEMBL4109221 | 0.69 | PGR (0.72) | PGRNR3C1AR | |
| SCHEMBL4109225 | 0.69 | PGR (0.72) | PGRNR3C1AR | |
| SCHEMBL4103309 | 0.68 | PGR (0.71) | PGRNR3C1AR | |
| SCHEMBL4103305 | 0.68 | PGR (0.71) | PGRNR3C1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355648-B1 | COMPOUNDS AS CONTRACEPTIVES AND PROGESTERONE ANTAGONIST | AMERICAN HOME PRODUCTS CORPORATION | 2002-03-12 | — | — | US | disclosed |