Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400454 | 0.80 | HRH3 (0.48) | GAANPSR1ALDH1A1MAPTATM | |
| SCHEMBL7684996 | 0.80 | GAA (0.42) | GAANPSR1ALDH1A1MAPT | |
| SCHEMBL9030284 | 0.79 | POLB (0.39) | GAANPSR1ALDH1A1MAPTATM | |
| Hydrochloric Acid SCHEMBL7684842 | 0.78 | NPSR1 (0.43) | GAANPSR1ALDH1A1MAPTATM | |
| Hydrochloric Acid SCHEMBL7680655 | 0.78 | POLB (0.38) | GAANPSR1ALDH1A1MAPTATM | |
| SCHEMBL7687050 | 0.75 | CYP2D6 (0.41) | GAAALDH1A1MAPTTSHRKDM4E | |
| SCHEMBL7680107 | 0.74 | GAA (0.38) | GAAALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL7676228 | 0.74 | CYP2D6 (0.40) | GAAALDH1A1MAPTTSHRKDM4E | |
| SCHEMBL9031736 | 0.72 | USP2 (0.35) | ALDH1A1MAPTATMPOLB | |
| Hydrochloric Acid SCHEMBL7686863 | 0.72 | CYP2D6 (0.38) | GAAALDH1A1MAPTTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472397-B1 | Nitrogen-containing heterocyclic compounds having antiplatelet aggregation effect and medicinal use thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-10-29 | — | — | US | disclosed |
| EP-1070712-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS HAVING ANTIPLATELET AGGREGATION EFFECT AND MEDICINAL USE THEREOF | MEIJI SEIKA KAISHA LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |