Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HRH2 | P25021 | 7/20 | 0.41 |
| ▸ | HRH1 | P35367 | 7/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.39 |
| ▸ | AOC2 | O75106 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364769 | 0.90 | MAPT (0.40) | GPR119ALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL7684334 | 0.80 | GAA (0.42) | GAAALDH1A1MAPTNPSR1 | |
| SCHEMBL7687431 | 0.80 | GPR119 (0.44) | GAAGPR119ALDH1A1MAPTKMT2A | |
| SCHEMBL9030284 | 0.77 | POLB (0.39) | GAAHRH2HRH1ALDH1A1MAPT | |
| SCHEMBL7400454 | 0.77 | HRH3 (0.48) | GAAHRH1ALDH1A1MAPTNPSR1 | |
| SCHEMBL9030646 | 0.77 | GPR119 (0.44) | HRH2HRH1GPR119SIRT3CYP2D6 | |
| Hydrochloric Acid SCHEMBL7680655 | 0.77 | POLB (0.38) | GAAALDH1A1MAPTNPSR1CYP2D6 | |
| SCHEMBL7681879 | 0.76 | CYP2D6 (0.38) | GAAHRH2HRH1ALDH1A1MAPT | |
| SCHEMBL12814098 | 0.76 | NPSR1 (0.55) | GAAGPR119ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7680850 | 0.76 | TP53 (0.43) | GPR119ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472397-B1 | Nitrogen-containing heterocyclic compounds having antiplatelet aggregation effect and medicinal use thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-10-29 | — | — | US | disclosed |
| EP-1070712-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS HAVING ANTIPLATELET AGGREGATION EFFECT AND MEDICINAL USE THEREOF | MEIJI SEIKA KAISHA LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |