Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 3/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7687237 | 0.86 | CNR1 (0.43) | ALDH1A1MAPTCYP3A4CPA1 | |
| SCHEMBL6492632 | 0.85 | ALDH1A1 (0.40) | ALDH1A1POLBMAPTCYP3A4CPA1 | |
| SCHEMBL121197 | 0.85 | ALDH1A1 (0.40) | ALDH1A1GAACYP3A4CPA1 | |
| SCHEMBL6489372 | 0.85 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2MAPTCYP3A4CPA1 | |
| SCHEMBL6477248 | 0.85 | CYP2C9 (0.45) | ALDH1A1SMN1; SMN2MAPTCYP3A4CPA1 | |
| SCHEMBL6487215 | 0.85 | ALDH1A1 (0.42) | ALDH1A1GAACYP3A4CPA1 | |
| SCHEMBL7680206 | 0.83 | PPARD (0.39) | ALDH1A1POLBCYP3A4CPA1 | |
| SCHEMBL6479508 | 0.83 | ALDH1A1 (0.38) | ALDH1A1POLBMAPTRAB9ACYP3A4 | |
| SCHEMBL7686449 | 0.83 | CYP2C19 (0.41) | ALDH1A1MAPT | |
| SCHEMBL7689051 | 0.82 | CNR1 (0.42) | ALDH1A1POLBSMN1; SMN2MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492392-B1 | INHIBITING TUMOR CELL PROLIFERATION | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-12-10 | — | — | US | disclosed |
| WO-2001085716-A1 | 2-PIPERIDONE COMPOUNDS FOR THE TREATMENT OF CANCER | KYOWA HAKKO KOGYO CO., LTD (JP) | 2001-11-15 | — | — | WO | disclosed |