Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121197 | 0.84 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7684336 | 0.83 | ALDH1A1 (0.40) | ALDH1A1MAPT | |
| SCHEMBL7687237 | 0.83 | CNR1 (0.43) | ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL6492632 | 0.82 | ALDH1A1 (0.40) | ALDH1A1MAPTNPSR1HTTL3MBTL1 | |
| SCHEMBL6487215 | 0.82 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL6477248 | 0.82 | CYP2C9 (0.45) | CYP2C19ALDH1A1MAPTKDM4ENPSR1 | |
| SCHEMBL6489372 | 0.82 | ALDH1A1 (0.40) | ALDH1A1MAPTNPSR1MEN1KMT2A | |
| SCHEMBL5280121 | 0.81 | CYP2C19 (0.51) | CYP2C19CYP1A2ALDH1A1MAPTHPGD | |
| SCHEMBL14582256 | 0.81 | MTNR1A (0.45) | CYP2C19CYP1A2ALDH1A1MAPTHPGD | |
| SCHEMBL5280903 | 0.81 | CYP2C19 (0.51) | CYP2C19CYP1A2ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492392-B1 | INHIBITING TUMOR CELL PROLIFERATION | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-12-10 | — | — | US | disclosed |
| WO-2001085716-A1 | 2-PIPERIDONE COMPOUNDS FOR THE TREATMENT OF CANCER | KYOWA HAKKO KOGYO CO., LTD (JP) | 2001-11-15 | — | — | WO | disclosed |