SCHEMBL7684463

SCHEMBL7684463

FC(F)C(F)(F)COc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CFTR P13569 2/20 0.47
HTT P42858 2/20 0.46
KMT2A Q03164 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
KCNA3 P22001 1/20 0.43
ALDH1A1 P00352 3/20 0.42
NPSR1 Q6W5P4 2/20 0.40
LMNA P02545 2/20 0.40
MEN1 O00255 1/20 0.40
TAAR1 Q96RJ0 1/20 0.39
RECQL P46063 1/20 0.39
USP2 O75604 1/20 0.39
MAPT P10636 1/20 0.39
TSHR P16473 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
SCN4A P35499 2/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14366584 0.86 LMNA (0.53) SMN1; SMN2LMNAMAPT
SCHEMBL12691118 0.84 PPARA (0.43) CFTRHTTKMT2ASMN1; SMN2ALDH1A1
SCHEMBL28473082 0.84 KCNA3 (0.40) CFTRHTTKMT2ASMN1; SMN2KCNA3
SCHEMBL3885645 0.80 HTT (0.47) HTTKMT2ASMN1; SMN2ALDH1A1USP2
SCHEMBL5430591 0.80 HTT (0.43) CFTRHTTKMT2ASMN1; SMN2ALDH1A1
SCHEMBL5384421 0.80 HTT (0.50) HTTKMT2ASMN1; SMN2ALDH1A1NPSR1
SCHEMBL1710061 0.80 KMT2A (0.51) CFTRHTTKMT2ASMN1; SMN2ALDH1A1
SCHEMBL7769868 0.80 HTT (0.47) CFTRHTTKMT2ASMN1; SMN2ALDH1A1
SCHEMBL6944585 0.80 HTT (0.47) CFTRHTTKMT2ASMN1; SMN2ALDH1A1
Hydrochloric Acid SCHEMBL9005029 0.79 SNCA (0.43) CFTRHTTKMT2ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111816935-A Method of charging secondary lithium metal batteries to reactivate dead lithium with redox shuttle additives and battery control system incorporating the method 麻省固能控股有限公司 2020-10-23 CN claimed
US-11693310-B2 Blue curable resin composition, blue color filter, and display device including same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-07-04 US disclosed
US-20200371435-A1 BLUE CURABLE RESIN COMPOSITION, BLUE COLOR FILTER, AND DISPLAY DEVICE INCLUDING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-11-26 US disclosed
CN-111816935-A Method of charging secondary lithium metal batteries to reactivate dead lithium with redox shuttle additives and battery control system incorporating the method 麻省固能控股有限公司 2020-10-23 CN disclosed
CN-111640973-A Rechargeable battery 麻省固能控股有限公司 2020-09-08 CN disclosed
US-6362206-B1 FUNGICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-03-26 US disclosed
US-6034248-A FUNGICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-03-07 US disclosed