Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 4/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684463 | 0.80 | CFTR (0.47) | HTTKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL693618 | 0.79 | MAPT (0.47) | HTTKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL4163859 | 0.79 | HTT (0.37) | HTTKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5610070 | 0.78 | HTT (0.41) | HTTKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8422629 | 0.78 | HTT (0.45) | HTTKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5982898 | 0.78 | HTT (0.36) | HTTKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1975332 | 0.78 | HTT (0.39) | HTTKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1710061 | 0.77 | KMT2A (0.51) | HTTKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6944585 | 0.77 | HTT (0.47) | HTTKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7769868 | 0.77 | HTT (0.47) | HTTKMT2ASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219216-A1 | 1-Alkylpiperazinyl-Pyrrolidin-2,5-Dione Derivatives as Adrenergic Receptor Antagonists | RANBAXY LABORATORIES LIMITED (IN) | 2007-09-20 | — | — | US | claimed |
| EP-1682145-A1 | 1-ALKYLPIPERAZINYL-PYRROLIDIN-2,5-DIONE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories Limited (IN) | 2006-07-26 | — | — | EP | claimed |
| WO-2005037282-A1 | 1-ALKYLPIPERAZINYL-PYRROLIDIN-2,5-DIONE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-04-28 | — | — | WO | claimed |
| US-6306880-B1 | HETEROCYCLIC ALCOHOL DERIVATIVES AS FUNGICIDES | SANKYO COMPANY, LIMITED (JP) | 2001-10-23 | — | — | US | claimed |
| EP-1033367-A2 | Process for the preparation of optically active triazole derivatives and their imidazolidin-2-one intermediates | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-09-06 | — | — | EP | claimed |
| EP-0884311-A2 | Triazole Derivatives and their production | Takeda Chemical Industries, Ltd. (JP) | 1998-12-16 | — | — | EP | claimed |
| EP-0617031-B1 | Orally active azole derivates | URIACH & CIA SA J (ES) | 1998-09-16 | — | — | EP | claimed |
| EP-0567982-B1 | Azole compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-07-01 | — | — | EP | claimed |
| US-5677464-A | Production of optically active triazole compounds and their intermediates | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-14 | — | — | US | claimed |
| US-5478826-A | Fungicides for human, animal and plants | J. URIACH & CIA. S.A. (ES) | 1995-12-26 | — | — | US | claimed |
| EP-0687672-A2 | Production of optically active triazole compounds and their intermediates | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-20 | — | — | EP | claimed |
| EP-0659751-A1 | Optically active azole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-06-28 | — | — | EP | claimed |
| US-5371101-A | Fungicides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | claimed |
| EP-0617031-A1 | Orally active azole derivates | J. URIACH & CIA. S.A. (ES) | 1994-09-28 | — | — | EP | claimed |
| EP-0567982-A1 | Azole compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1993-11-03 | — | — | EP | claimed |
| EP-2927218-B1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-07-04 | — | — | EP | disclosed |
| US-9725423-B2 | Tetrazolinone compound and applications thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-08 | — | — | US | disclosed |
| EP-0332387-B1 | Triazole derivatives, their preparation and their use as fungicides | SANKYO CO (JP) | 1993-11-24 | — | — | EP | disclosed |
| EP-0480215-A1 | New sulfonamides as antifungal agents | J. URIACH & CIA. S.A. (ES) | 1992-04-15 | — | — | EP | disclosed |
| EP-0332387-A1 | Triazole derivatives, their preparation and their use as fungicides | Sankyo Company Limited (JP) | 1989-09-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219216-A1 | 1-Alkylpiperazinyl-Pyrrolidin-2,5-Dione Derivatives as Adrenergic Receptor Antagonists | ADRA1D, ADRA1A, ADRB1 | HTT 3944/4885KMT2A 3012/4885SMN1; SMN2 4348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.