Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676228 | 0.91 | CYP2D6 (0.40) | ACHEALDH1A1CYP2D6HRH3KDM4E | |
| SCHEMBL7680314 | 0.91 | ACHE (0.37) | ACHEALDH1A1CYP2D6HRH3KDM4E | |
| SCHEMBL7687105 | 0.89 | HRH3 (0.35) | ACHEALDH1A1CYP2D6HRH3KDM4E | |
| Hydrochloric Acid SCHEMBL7687054 | 0.89 | HRH3 (0.35) | ACHEALDH1A1CYP2D6HRH3KDM4E | |
| SCHEMBL7680937 | 0.88 | RAB9A (0.36) | ACHEALDH1A1CYP2D6HRH3KDM4E | |
| SCHEMBL7686580 | 0.88 | ACHE (0.33) | ACHEALDH1A1CYP2D6HRH3KDM4E | |
| Hydrochloric Acid SCHEMBL7687046 | 0.87 | RAB9A (0.37) | ACHEALDH1A1CYP2D6HRH3KDM4E | |
| SCHEMBL7684757 | 0.86 | ACHE (0.37) | ACHEALDH1A1HRH3KDM4ETDP1 | |
| SCHEMBL7680850 | 0.86 | TP53 (0.43) | ACHEALDH1A1KDM4ETP53 | |
| SCHEMBL7684783 | 0.83 | ACHE (0.35) | ACHEALDH1A1CYP2D6HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472397-B1 | Nitrogen-containing heterocyclic compounds having antiplatelet aggregation effect and medicinal use thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-10-29 | — | — | US | disclosed |
| EP-1070712-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS HAVING ANTIPLATELET AGGREGATION EFFECT AND MEDICINAL USE THEREOF | MEIJI SEIKA KAISHA LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |