Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.35 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.33 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684518 | 1.00 | CA9 (0.44) | CA9MAPTL3MBTL1MAP3K7TAB1 | |
| SCHEMBL7979226 | 0.93 | MAPT (0.38) | CA9MAPTL3MBTL1KCNN4ALDH1A1 | |
| SCHEMBL7979224 | 0.93 | MAPT (0.38) | CA9MAPTL3MBTL1KCNN4ALDH1A1 | |
| SCHEMBL7684170 | 0.92 | MAPT (0.42) | CA9MAPTL3MBTL1KCNN4ALDH1A1 | |
| SCHEMBL7690667 | 0.92 | MAPT (0.39) | CA9MAPTL3MBTL1KCNN4ALDH1A1 | |
| SCHEMBL7684744 | 0.92 | MAPT (0.39) | CA9MAPTL3MBTL1KCNN4ALDH1A1 | |
| SCHEMBL7684749 | 0.92 | MAPT (0.39) | CA9MAPTL3MBTL1KCNN4ALDH1A1 | |
| SCHEMBL7684171 | 0.92 | MAPT (0.42) | CA9MAPTL3MBTL1KCNN4ALDH1A1 | |
| SCHEMBL7690669 | 0.92 | MAPT (0.39) | CA9MAPTL3MBTL1KCNN4ALDH1A1 | |
| SCHEMBL7691157 | 0.92 | MAPT (0.55) | CA9MAPTL3MBTL1KCNN4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020137929-A1 | 1 - (3-heterocyclylphenyl) isothiourea, -isourea, -guanidine and -amidine herbicidal agents | INTELLECTUAL PROPERTY DEPARTMENT, BASF AKTIENGESELLSCHAFT (DE) | 2002-09-26 | — | — | US | disclosed |
| US-6303783-B1 | 1- (3-Heterocyclylphenyl) isothiourea, -isourea, -guanidine and -amidine herbicidal agents | AMERICAN CYANAMID CO. | 2001-10-16 | — | — | US | disclosed |
| EP-0985670-A1 | 1-(3-Heterocyclylphenyl)isothiourea, -isourea, -guanidine and -amidine compounds as herbicides | American Cyanamid Company (US) | 2000-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020137929-A1 | 1 - (3-heterocyclylphenyl) isothiourea, -isourea, -guanidine and -amidine herbicidal agents | IMPDH1, GANC, DDT | CA9 2819/4885MAPT 3732/4885L3MBTL1 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.