Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7687350 | 0.87 | L3MBTL1 (0.47) | TSHRSMN1; SMN2MAPTALDH1A1TP53 | |
| SCHEMBL7685106 | 0.84 | SMN1; SMN2 (0.34) | DHODHTSHRSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7558733 | 0.84 | KMT2A (0.36) | DHODHTSHRSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL8492662 | 0.80 | LMNA (0.43) | DHODHTAS1R3TAS1R1TAS1R2LMNA | |
| SCHEMBL7559185 | 0.78 | TYK2 (0.36) | DHODHTSHRMAPTTP53GAA | |
| SCHEMBL8747888 | 0.78 | KDM4E (0.37) | DHODHALDH1A1L3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL7575701 | 0.77 | HCRTR2 (0.40) | DHODHSMN1; SMN2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9323629 | 0.77 | DHODH (0.35) | DHODHSMN1; SMN2L3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL8814987 | 0.76 | CSF1R (0.45) | DHODHALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7555057 | 0.76 | TYK2 (0.36) | DHODHALDH1A1L3MBTL1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020045551-A1 | 4-benzoyl isoxazoles derivatives and their use as herbicides | MUSIL TIBOR (GB) | 2002-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045551-A1 | 4-benzoyl isoxazoles derivatives and their use as herbicides | CBR3, CBR1, GLRA3 | DHODH 3856/4885TSHR 174/4885SMN1; SMN2 3433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.