Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7627479 | 0.83 | HTR2A (0.41) | DPP9DPP7HTR2ADRD2SLC6A2 | |
| SCHEMBL6153867 | 0.83 | HTR2A (0.41) | DPP9DPP7HTR2ADRD2SLC6A2 | |
| SCHEMBL761583 | 0.83 | HTR2A (0.41) | DPP9DPP7HTR2ADRD2SLC6A2 | |
| Hydrochloric Acid SCHEMBL6196871 | 0.82 | HTR2A (0.40) | DPP9DPP7HTR2ADRD2SLC6A2 | |
| Hydrochloric Acid SCHEMBL7498632 | 0.82 | HTR2A (0.40) | DPP9DPP7HTR2ADRD2SLC6A2 | |
| SCHEMBL4867850 | 0.70 | RBP4 (0.38) | MAPK1USP2CYP2C19 | |
| Mandelic Acid SCHEMBL27837822 | 0.68 | LMNA (0.67) | LMNAMAPK1CYP2D6HPGDCES2 | |
| Mandelic Acid SCHEMBL27563685 | 0.67 | LMNA (0.95) | LMNAMAPK1CYP2D6HPGDCES2 | |
| Mandelic Acid SCHEMBL27603168 | 0.66 | LMNA (0.62) | LMNAMAPK1CYP2D6HPGDCES2 | |
| Mandelic Acid SCHEMBL29777368 | 0.66 | LMNA (1.00) | LMNAMAPK1CYP2D6HPGDCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362179-B1 | PSYCHOLOGICAL DISORDERS; NERVOUS SYSTEM DISORDERS | SANKYO COMPANY, LIMITED (JP) | 2002-03-26 | — | — | US | disclosed |