SCHEMBL7685019

SCHEMBL7685019

C[C@H](O)C(=O)c1ccccc1F

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 5/20 0.61
CES1 P23141 5/20 0.61
ALDH1A1 P00352 3/20 0.52
ALOX15 P16050 1/20 0.52
GAA P10253 1/20 0.52
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
POLB P06746 1/20 0.47
TDP1 Q9NUW8 1/20 0.46
ADRB2 P07550 1/20 0.45
ADRB1 P08588 1/20 0.45
ADRB3 P13945 1/20 0.45
NPC1 O15118 2/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
PTPN1 P18031 1/20 0.43
ERCC5 P28715 1/20 0.43
FEN1 P39748 1/20 0.43
BCHE P06276 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30081009 0.85 CES2 (0.58) CES2CES1ALDH1A1ALOX15GAA
SCHEMBL888679 0.85 CES2 (0.58) CES2CES1ALDH1A1ALOX15GAA
SCHEMBL5224837 0.83 CES2 (0.56) CES2CES1ALDH1A1ALOX15GAA
SCHEMBL11769973 0.82 ALDH1A1 (0.55) CES2CES1ALDH1A1ALOX15GAA
SCHEMBL1155548 0.82 CES2 (0.55) CES2CES1ALDH1A1ALOX15GAA
SCHEMBL9017503 0.80 CES2 (0.53) CES2CES1ALDH1A1ALOX15GAA
Isopropyl Alcohol SCHEMBL29078917 0.79 CES2 (0.56) CES2CES1ALDH1A1ALOX15GAA
SCHEMBL27995319 0.79 CES2 (0.61) CES2CES1ALDH1A1ALOX15GAA
SCHEMBL19333968 0.79 CES2 (0.51) CES2CES1ALDH1A1ALOX15GAA
SCHEMBL28380256 0.79 CES2 (0.51) CES2CES1ALDH1A1ALOX15GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6362206-B1 FUNGICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-03-26 US disclosed
EP-1033367-A2 Process for the preparation of optically active triazole derivatives and their imidazolidin-2-one intermediates TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-09-06 EP disclosed
US-6034248-A FUNGICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-03-07 US disclosed
US-5677464-A Production of optically active triazole compounds and their intermediates TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-10-14 US disclosed
EP-0687672-A2 Production of optically active triazole compounds and their intermediates TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-12-20 EP disclosed