SCHEMBL7685032

SCHEMBL7685032

COc1[c]cc(Br)cc1C

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6286491 0.80 HSD17B10 (0.33)
SCHEMBL28179999 0.78 ERN1 (0.35) NQO2
SCHEMBL357984 0.77 ACHE (0.31)
SCHEMBL29134461 0.77
SCHEMBL29134432 0.77
SCHEMBL3340143 0.76 FFAR4 (0.32)
SCHEMBL2154934 0.76 ALDH1A1 (0.38)
SCHEMBL3410424 0.75 S1PR1 (0.35)
SCHEMBL29250181 0.72 POLB (0.35)
SCHEMBL4061096 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6436961-B1 SUBSTANCE P RECEPTOR ANTAGONIST; 2-PHENYL-3-BENZYLAMINOPIPERIDINES PFIZER INC 2002-08-20 US claimed
CN-117120429-A KHK inhibitor 吉利德科学公司 2023-11-24 CN disclosed