SCHEMBL7685063

SCHEMBL7685063

CC(C)(OOC=CCOC(=O)O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.46
ALDH1A1 P00352 4/20 0.40
ALOX15 P16050 1/20 0.40
CYP2C19 P33261 1/20 0.37
HIF1A Q16665 1/20 0.37
TSHR P16473 2/20 0.34
KMT2A Q03164 2/20 0.34
MAPT P10636 1/20 0.34
CHRM2 P08172 2/20 0.34
CHRM4 P08173 2/20 0.34
CHRM5 P08912 2/20 0.34
CHRM1 P11229 2/20 0.34
CHRM3 P20309 2/20 0.34
KCNN4 O15554 1/20 0.33
AKT1 P31749 1/20 0.33
HTT P42858 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2772376 0.80 MAPK1 (0.43) MAPK1ALDH1A1ALOX15CYP2C19HIF1A
SCHEMBL464831 0.77
SCHEMBL7692610 0.75 MAPK1 (0.41) MAPK1ALDH1A1ALOX15CYP2C19HIF1A
SCHEMBL9242885 0.74 MAPK1 (0.43) MAPK1ALDH1A1ALOX15CYP2C19HIF1A
SCHEMBL10435073 0.73 MAPK1 (0.42) MAPK1ALDH1A1ALOX15CYP2C19HIF1A
SCHEMBL3760909 0.73
SCHEMBL28228336 0.73 MAPK1 (0.53) MAPK1ALDH1A1ALOX15CYP2C19TSHR
SCHEMBL10697394 0.72 MAPK1 (0.36) MAPK1ALDH1A1ALOX15CHRM2CHRM1
SCHEMBL10698412 0.72 MAPK1 (0.41) MAPK1ALDH1A1ALOX15CYP2C19HIF1A
SCHEMBL7692278 0.71 MAPK1 (0.43) MAPK1ALDH1A1ALOX15CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5140083-A Copolymerized with an unsaturated peroxycarbonate or peroxyester; molding materials; materials handling; heat resistance, impact strength; storage stability NIPPON OIL AND FATS CO., LTD. (JP) 1992-08-18 US claimed
EP-3284784-A1 METHACRYLIC RESIN COMPOSITION Kuraray Co., Ltd. (JP) 2018-02-21 EP disclosed
US-6335401-B1 ADHESION PRIMER ATOFINA (FR) 2002-01-01 US disclosed
US-5674930-A MOLDING MATERIAL COMPRISING A BLEND OF A PROPYLENE BASED POLYMER AND A GRAFT ADDITION COPOLYMER; IMPACT STRENGTH, COATABILITY; BUMPER OF AUTOMOBILE NOF CORPORATION (JP) 1997-10-07 US disclosed
EP-0608856-B1 Graft precursor and process for producing grafted aromatic polycarbonate resin MITSUBISHI GAS CHEMICAL CO (JP) 1997-07-09 EP disclosed
EP-0507561-B1 Thermoplastic resin compositions NOF CORP (JP) 1996-06-26 EP disclosed
EP-0435340-B1 Thermoplastic resin compositions NIPPON PETROCHEMICALS CO LTD (JP) 1996-05-01 EP disclosed
EP-0423767-B1 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO LTD (JP) 1996-03-06 EP disclosed
EP-0338303-B1 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO LTD (JP) 1995-11-15 EP disclosed
US-5438108-A Melt-kneading a mixture of aromatic polycarbonate resin and vinylic copolymer containing active oxygen; optical distortion reduction MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1995-08-01 US disclosed
EP-0361400-A2 Thermoplastic resin composition NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1990-04-04 EP disclosed
EP-0338303-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO., LTD. (JP) 1989-10-25 EP disclosed
EP-0338544-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-10-25 EP disclosed
EP-0334296-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-09-27 EP disclosed
EP-0314188-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO., LTD. (JP) 1989-05-03 EP disclosed
EP-0307802-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-03-22 EP disclosed
EP-0304039-A2 Thermoplastic resin composition. NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-02-22 EP disclosed
EP-0304041-A2 Thermoplastic resin composition. NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-02-22 EP disclosed
EP-0304040-A2 Thermoplastic resin composition. NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-02-22 EP disclosed
EP-0295706-A2 Thermoplastic resin composition and method for preparing the same Nippon Petrochemicals Co., Ltd. (JP) 1988-12-21 EP disclosed