SCHEMBL2772376

SCHEMBL2772376

CC(C)(OOC=CC(=O)OCCOC(=O)O)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.43
HCAR2 Q8TDS4 2/20 0.42
AKR1B10 O60218 5/20 0.40
AKR1B1 P15121 5/20 0.40
ALDH1A1 P00352 3/20 0.38
ALOX15 P16050 3/20 0.38
MAOB P27338 1/20 0.37
THRB P10828 1/20 0.36
ALOX5 P09917 3/20 0.36
TTR P02766 2/20 0.36
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRM3 P20309 1/20 0.35
APP P05067 2/20 0.35
CYP3A4 P08684 2/20 0.35
ALOX12 P18054 2/20 0.35
HSD17B10 Q99714 2/20 0.35
CYP2C19 P33261 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10435073 0.90 MAPK1 (0.42) MAPK1HCAR2AKR1B10AKR1B1ALDH1A1
SCHEMBL8525638 0.87 HCAR2 (0.37) MAPK1HCAR2AKR1B10AKR1B1ALDH1A1
SCHEMBL7692322 0.87 HCAR2 (0.35) MAPK1HCAR2AKR1B10AKR1B1ALDH1A1
SCHEMBL9242885 0.86 MAPK1 (0.43) MAPK1HCAR2AKR1B10AKR1B1ALDH1A1
SCHEMBL4224940 0.86 CYP2D6 (0.38) MAPK1HCAR2AKR1B10AKR1B1ALDH1A1
SCHEMBL9862015 0.84 HCAR2 (0.35) MAPK1HCAR2AKR1B10AKR1B1ALDH1A1
SCHEMBL8761490 0.83 CYP2D6 (0.36) MAPK1HCAR2ALDH1A1HIF1AKDM4E
SCHEMBL7692278 0.81 MAPK1 (0.43) MAPK1ALDH1A1ALOX15HSD17B10CYP2C19
SCHEMBL10697394 0.80 MAPK1 (0.36) MAPK1HCAR2ALDH1A1ALOX15CHRM2
SCHEMBL7685063 0.80 MAPK1 (0.46) MAPK1ALDH1A1ALOX15CHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5140083-A Copolymerized with an unsaturated peroxycarbonate or peroxyester; molding materials; materials handling; heat resistance, impact strength; storage stability NIPPON OIL AND FATS CO., LTD. (JP) 1992-08-18 US claimed
CN-107531978-B Methacrylic resin composition 株式会社可乐丽 2020-11-03 CN disclosed
EP-3284784-A1 METHACRYLIC RESIN COMPOSITION Kuraray Co., Ltd. (JP) 2018-02-21 EP disclosed
EP-0650987-B1 Adhesive fluorine-containing polymer and laminate employing it ASAHI GLASS CO LTD (JP) 2010-04-28 EP disclosed
WO-2009100986-A1 BIOCIDAL COMPOSITIONS FOR PLASTICS BASF SE (DE) 2009-08-20 WO disclosed
US-6476125-B1 Fluorine-containing polymer alloy, and method for its preparation and method for its molding ASAHI GLASS COMPANY LTD. (JP) 2002-11-05 US disclosed
US-6335401-B1 ADHESION PRIMER ATOFINA (FR) 2002-01-01 US disclosed
EP-0761757-B1 Fluorine-containing polymer alloy, and method for its preparation and method for its molding ASAHI GLASS CO LTD (JP) 1999-12-01 EP disclosed
US-5965275-A Adhesive fluorine-containing polymer and laminate employing it ASAHI GLASS COMPANY LTD. (JP) 1999-10-12 US disclosed
US-5736610-A Adhesive fluorine-containing polymer and laminate employing it ASAHI GLASS COMPANY LTD. (JP) 1998-04-07 US disclosed
EP-0304039-A2 Thermoplastic resin composition. NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-02-22 EP disclosed
EP-0304041-A2 Thermoplastic resin composition. NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-02-22 EP disclosed
EP-0304040-A2 Thermoplastic resin composition. NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-02-22 EP disclosed
EP-0295706-A2 Thermoplastic resin composition and method for preparing the same Nippon Petrochemicals Co., Ltd. (JP) 1988-12-21 EP disclosed
EP-0289933-A2 Graft polymerization precurser and method manufacturing the same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-11-09 EP disclosed
EP-0279430-A2 The method of manufacturing a grafted resin composition NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-08-24 EP disclosed
US-4665132-A CONTAINING PEROXY GROUPS NIPPON OIL & FATS CO., LTD. (JP) 1987-05-12 US disclosed
US-4665131-A CONTAINING PEROXYCARBONATE GROUPS NIPPON OIL AND FATS COMPANY, LTD. (JP) 1987-05-12 US disclosed
EP-0206645-A2 Block copolymer NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1986-12-30 EP disclosed
EP-0206644-A2 Block copolymer NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1986-12-30 EP disclosed