Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2772376 | 0.76 | MAPK1 (0.43) | MAPK1ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL9242885 | 0.73 | MAPK1 (0.43) | MAPK1ALDH1A1TSHRALOX15CYP2C19 | |
| SCHEMBL7692278 | 0.73 | MAPK1 (0.43) | MAPK1ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL7685063 | 0.72 | MAPK1 (0.46) | MAPK1ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL10435073 | 0.72 | MAPK1 (0.42) | MAPK1ALDH1A1ALOX15CYP2C19HIF1A | |
| SCHEMBL9862043 | 0.72 | MAPK1 (0.39) | MAPK1ALDH1A1TDP1ALOX15MAPT | |
| SCHEMBL8526043 | 0.70 | MAPK1 (0.43) | MAPK1ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL10477188 | 0.70 | MAPK1 (0.40) | MAPK1ALDH1A1TSHRALOX15CES1 | |
| SCHEMBL9862015 | 0.70 | HCAR2 (0.35) | MAPK1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL8740112 | 0.69 | MAPK1 (0.57) | MAPK1ALDH1A1TSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277608-A2 | Graft polymerization preformer and method of manufacturing the same | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1988-08-10 | — | — | EP | disclosed |