Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 3/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.41 |
| ▸ | HTR3B | O95264 | 2/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7685070 | 1.00 | KDM4E (0.51) | KDM4EALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL16255877 | 1.00 | KDM4E (0.51) | KDM4EALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL7297926 | 0.79 | KDM4E (0.62) | KDM4EALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL30467838 | 0.79 | KDM4E (0.62) | KDM4EALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7682424 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL7682428 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL30251861 | 0.75 | KDM4E (0.62) | KDM4EALDH1A1NPSR1CYP3A4TSHR | |
| SCHEMBL496589 | 0.75 | KDM4E (0.62) | KDM4EALDH1A1NPSR1CYP3A4TSHR | |
| SCHEMBL19150070 | 0.75 | KDM4E (0.54) | KDM4EALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL28478339 | 0.74 | KDM4E (0.43) | KDM4EALDH1A1LMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6462039-B1 | SUCH AS O-(2-((5,6-DIHYDRO-(1,4,2)DIOXAZIN-3-YL)-METHOXY-IMINOMETHYL)-BENZYL)1-(1 -METHYL-1H-INDAZOL-3-YL)ETHANONEOXIME; WELL TOLERATED BY PLANTS; CONTROLLING PLANT DISEASES BY TREATMENT OF AERIAL PARTS, SEEDS OR SOIL | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |