Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 3/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.49 |
| ▸ | HTR3B | O95264 | 2/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.49 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30251861 | 1.00 | KDM4E (0.62) | KDM4ECYP3A4TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL1563376 | 0.98 | KDM4E (0.60) | KDM4ECYP3A4TSHRALDH1A1MAPK1 | |
| SCHEMBL27677437 | 0.89 | CYP3A4 (0.54) | KDM4ECYP3A4TSHRALDH1A1MAPK1 | |
| SCHEMBL7299469 | 0.88 | KDM4E (0.54) | KDM4ECYP3A4TSHRALDH1A1MAPK1 | |
| SCHEMBL7297926 | 0.85 | KDM4E (0.62) | KDM4ECYP3A4TSHRALDH1A1MAPK1 | |
| SCHEMBL30467838 | 0.85 | KDM4E (0.62) | KDM4ECYP3A4TSHRALDH1A1MAPK1 | |
| SCHEMBL260569 | 0.84 | KDM4E (0.60) | KDM4ECYP3A4TSHRALDH1A1MAPK1 | |
| SCHEMBL992781 | 0.84 | KDM4E (0.60) | KDM4ECYP3A4TSHRALDH1A1MAPK1 | |
| SCHEMBL29789796 | 0.84 | KDM4E (0.60) | KDM4ECYP3A4TSHRALDH1A1MAPK1 | |
| SCHEMBL31632586 | 0.84 | KDM4E (0.60) | KDM4ECYP3A4TSHRALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 724 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111511731-B | Olefin compounds as modulators of the farnesol X receptor | 百时美施贵宝公司 | 2023-05-23 | — | — | CN | claimed |
| CN-114980550-B | Circuit board ink stripping agent and circuit board ink stripping method | 昆山市板明电子科技有限公司 | 2022-11-22 | — | — | CN | claimed |
| CN-114980550-A | Circuit board ink stripping agent and circuit board ink stripping method | 昆山市板明电子科技有限公司 | 2022-08-30 | — | — | CN | claimed |
| US-20220096454-A1 | CARBOXYLIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2022-03-31 | — | — | US | claimed |
| CN-108350034-B | Antimicrobial polymyxin derived compounds | 莫纳什大学 | 2022-03-11 | — | — | CN | claimed |
| CN-109589271-A | A kind of high moisturizing Face-protecting mask and preparation method thereof | 晏玉 | 2019-04-09 | — | — | CN | claimed |
| EP-2200440-B1 | ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS | CRESTONE INC (US) | 2017-07-19 | — | — | EP | claimed |
| CN-106008540-A | Heterocyclic aromatic acid ester type podophyllotoxin derivatives with anti-tumor activity as well as preparation method and application | 遵义医学院 | 2016-10-12 | — | — | CN | claimed |
| CN-103787978-A | Synthesis method of 1-methylindazole-3-formic acid | ZHANGJIAGANG JIUMU TECHNOLOGY CO LTD | 2014-05-14 | — | — | CN | claimed |
| US-8598353-B2 | Benzazole derivatives, compositions, and methods of use as β-secretase inhibitors | HIGH POINT PHARMACEUTICALS, LLC (US) | 2013-12-03 | — | — | US | claimed |
| US-20040248960-A1 | Process for preparing 1-methylindazole-3-carboxylic acid | CHEMAGIS LTD. (IL) | 2004-12-09 | — | — | US | claimed |
| EP-1484321-A1 | Process for preparing 1-methylindazole-3-carboxylic acid | Chemagis Ltd. (IL) | 2004-12-08 | — | — | EP | claimed |
| CN-1429816-A | New method of preparing Granisetron intermediate | NINGBO TIANHENG PHARMACEUTICAL (CN) | 2003-07-16 | — | — | CN | claimed |
| EP-0772613-B1 | PROCESS FOR THE PRODUCTION OF AMINOAZOBICYCLOALKANES FROM OXIMES | HOFFMANN LA ROCHE (CH) | 2001-11-21 | — | — | EP | claimed |
| WO-2001055109-A1 | AROMATIC AMIDES ACTING ON MELANOCORTIN RECEPTORS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | claimed |
| EP-0323105-B1 | Process for the preparation of 3-methylindazole-3-carboxylic acid | BEECHAM GROUP PLC (GB) | 1999-10-20 | — | — | EP | claimed |
| US-5856489-A | Process for the production of aminoazobicycloalkanes from oximes | SMITHKLINE BEECHAM P.L.C. (GB) | 1999-01-05 | — | — | US | claimed |
| EP-0772613-A2 | PROCESS FOR THE PRODUCTION OF AMINOAZOBICYCLOALKANES FROM OXIMES | SMITHKLINE BEECHAM PLC (GB) | 1997-05-14 | — | — | EP | claimed |
| WO-1996003401-A2 | PROCESS FOR THE PRODUCTION OF AMINOAZOBICYCLOALKANES FROM OXIMES | SMITHKLINE BEECHAM PLC (GB) | 1996-02-08 | — | — | WO | claimed |
| EP-0323105-A1 | Novel process | BEECHAM GROUP PLC (GB) | 1989-07-05 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220096454-A1 | CARBOXYLIC ACID DERIVATIVES | IRAK1, TANK, TRAF6 | KDM4E 563/4885CYP3A4 2752/4885TSHR 1999/4885 |
| US-20040248960-A1 | Process for preparing 1-methylindazole-3-carboxylic acid | CYP3A43, CMA1, CYP3A7 | KDM4E 1437/4885CYP3A4 5/4885TSHR 2636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.