Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673460 | 0.90 | ADRA2A (0.43) | HTR1AADRA2AADRA2BADRA2CHTR7 | |
| SCHEMBL248866 | 0.86 | ADRA2A (0.49) | HTR1AADRA2AADRA2BADRA2CHTR7 | |
| SCHEMBL29637386 | 0.86 | ADRA2A (0.49) | HTR1AADRA2AADRA2BADRA2CHTR7 | |
| SCHEMBL4182858 | 0.84 | HTR1A (0.42) | HTR1AADRA2AADRA2BADRA2CHTR7 | |
| SCHEMBL4093439 | 0.84 | HTR1A (0.47) | HTR1AADRA2AADRA2BADRA2CHTR7 | |
| SCHEMBL17386433 | 0.82 | HTR1A (0.46) | HTR1AADRA2AADRA2BADRA2CHTR7 | |
| SCHEMBL22823665 | 0.82 | HTR1A (0.46) | HTR1AADRA2AADRA2BADRA2CHTR7 | |
| SCHEMBL14476208 | 0.80 | HTR1A (0.45) | HTR1AADRA2AADRA2BADRA2CHTR7 | |
| SCHEMBL14460702 | 0.80 | HTR1A (0.45) | HTR1AADRA2AADRA2BADRA2CHTR7 | |
| SCHEMBL23644285 | 0.79 | MCHR1 (0.45) | HTR1AADRA2AADRA2BADRA2CHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444717-B1 | Foamed polyester resins with flame retardant properties | SINCO RICERCHE S.P.A. (IT) | 2002-09-03 | — | — | US | disclosed |