Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.75 |
| ▸ | MEN1 | O00255 | 8/20 | 0.75 |
| ▸ | MAPT | P10636 | 7/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.75 |
| ▸ | LMNA | P02545 | 5/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.75 |
| ▸ | NPC1 | O15118 | 3/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.75 |
| ▸ | RAB9A | P51151 | 2/20 | 0.75 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.75 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | GALK1 | P51570 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727216 | 1.00 | KMT2A (0.75) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL9651820 | 0.91 | KMT2A (0.71) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL9651814 | 0.91 | KMT2A (0.71) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL9524411 | 0.88 | KMT2A (0.66) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL10422268 | 0.88 | KMT2A (0.66) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL7685215 | 0.88 | KMT2A (0.64) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL7685217 | 0.88 | KMT2A (0.64) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL9817985 | 0.84 | KMT2A (0.57) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL9525748 | 0.84 | ALDH1A1 (0.57) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL11895851 | 0.82 | KDM4E (0.61) | KMT2AMEN1MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274642-B1 | HERBICIDAL AND FUNGICIDAL AGENTS BASED ON SUBSTITUTED PYRAZOLIN-5-ONE DERIVATIVES | BAYER AG (DE) | 1993-08-11 | — | — | EP | claimed |
| US-5162528-A | Pre- and post-emergence; phytaphthora in tomato plants; rice and wheat | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-10 | — | — | US | claimed |
| EP-0274642-B1 | HERBICIDAL AND FUNGICIDAL AGENTS BASED ON SUBSTITUTED PYRAZOLIN-5-ONE DERIVATIVES | BAYER AG (DE) | 1993-08-11 | — | — | EP | disclosed |