Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 5/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680746 | 1.00 | HDAC4 (0.36) | HDAC4OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL7680744 | 1.00 | HDAC4 (0.36) | HDAC4OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL8581476 | 1.00 | HDAC4 (0.36) | HDAC4OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL7685457 | 1.00 | HDAC4 (0.36) | HDAC4OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL7685460 | 1.00 | HDAC4 (0.36) | HDAC4OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL938767 | 0.79 | CES2 (0.35) | KMT2A | |
| SCHEMBL1828149 | 0.79 | HCAR3 (0.38) | HDAC4HCAR2BACE1BACE2KMT2A | |
| SCHEMBL939090 | 0.79 | HCAR3 (0.38) | HDAC4HCAR2BACE1BACE2KMT2A | |
| SCHEMBL20970623 | 0.79 | HCAR3 (0.38) | HDAC4HCAR2BACE1BACE2KMT2A | |
| SCHEMBL1828008 | 0.79 | HCAR3 (0.38) | HDAC4HCAR2BACE1BACE2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362206-B1 | FUNGICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-26 | — | — | US | disclosed |
| US-6034248-A | FUNGICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-03-07 | — | — | US | disclosed |
| EP-0657449-B1 | Azole compounds, their production and use as antifungal agents | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-04-08 | — | — | EP | disclosed |
| US-5545652-A | Triazole and imidazole compounds and their use as antifungal therapeutic agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-13 | — | — | US | disclosed |
| EP-0657449-A1 | Azole compounds, their production and use as antifungal agents | Takeda Chemical Industries, Ltd. (JP) | 1995-06-14 | — | — | EP | disclosed |