Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 18/20 | 0.40 |
| ▸ | RARG | P13631 | 15/20 | 0.40 |
| ▸ | PPARG | P37231 | 13/20 | 0.40 |
| ▸ | RARA | P10276 | 6/20 | 0.37 |
| ▸ | RARB | P10826 | 6/20 | 0.37 |
| ▸ | RXRB | P28702 | 4/20 | 0.37 |
| ▸ | RXRG | P48443 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567145 | 0.91 | RXRA (0.50) | RXRARARGPPARGRARARARB | |
| SCHEMBL7685302 | 0.91 | RXRA (0.50) | RXRARARGPPARGRARARARB | |
| SCHEMBL7686291 | 0.86 | RARG (0.49) | RXRARARGPPARGRARARARB | |
| SCHEMBL7686290 | 0.86 | RARG (0.49) | RXRARARGPPARGRARARARB | |
| SCHEMBL7686292 | 0.86 | RARG (0.49) | RXRARARGPPARGRARARARB | |
| SCHEMBL7685332 | 0.85 | RXRA (0.44) | RXRARARGPPARGRARARARB | |
| SCHEMBL7685327 | 0.85 | RXRA (0.44) | RXRARARGPPARGRARARARB | |
| SCHEMBL7685593 | 0.81 | RARA (0.41) | RARGRARARARB | |
| SCHEMBL7684901 | 0.81 | RARA (0.43) | RXRARARGPPARGRARARARB | |
| SCHEMBL7689448 | 0.80 | RARG (0.46) | RXRARARGPPARGRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37947-E1 | Aromatic polyenic compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 2002-12-31 | — | — | US | disclosed |
| US-5705167-A | TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, BONE AND OPHTHALMOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-01-06 | — | — | US | disclosed |