Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 3/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 3/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345782 | 1.00 | SMN1; SMN2 (0.33) | SMN1; SMN2MMP8MMP3TSHRKCNQ1 | |
| SCHEMBL7060241 | 0.93 | MMP8 (0.36) | MMP8MMP3MMP13MMP12ALDH1A1 | |
| SCHEMBL7055859 | 0.89 | MMP13 (0.39) | SMN1; SMN2TSHRKCNQ1HCRTR1HCRTR2 | |
| SCHEMBL7056949 | 0.88 | SMN1; SMN2 (0.35) | SMN1; SMN2MMP8KCNQ1HCRTR1HCRTR2 | |
| SCHEMBL7060386 | 0.86 | SMN1; SMN2 (0.35) | SMN1; SMN2TSHRKCNQ1HCRTR1HCRTR2 | |
| SCHEMBL7061603 | 0.85 | MMP13 (0.38) | SMN1; SMN2MMP8MMP3KCNQ1HCRTR1 | |
| SCHEMBL7352706 | 0.85 | MMP13 (0.34) | SMN1; SMN2MMP8MMP3TSHRKCNQ1 | |
| SCHEMBL7055448 | 0.85 | HTR2B (0.32) | SMN1; SMN2MMP13 | |
| SCHEMBL7346070 | 0.84 | MMP8 (0.46) | MMP8MMP3MMP13MMP12 | |
| SCHEMBL7053257 | 0.84 | SMN1; SMN2 (0.37) | SMN1; SMN2MMP8KCNQ1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489324-B2 | TREATING STROKE, ARHTRITIS, CANCER, TISSUE ULCERATION, DECUBITIS ULCER, RESTENOSIS, PERIODONTAL DISEASE, EPIDERMOLYSIS BULLOSA, SCLERITIS, PSORIASIS, AIDS, SEPSIS, AND SEPTIC SHOCK. | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-03 | — | — | US | disclosed |