Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.57 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811054 | 0.83 | NAMPT (0.54) | PTK2KCNK3KCNK9KMT2AMEN1 | |
| SCHEMBL2829176 | 0.83 | POLB (0.56) | RXFP1KMT2AMEN1F10NAMPT | |
| SCHEMBL13949629 | 0.82 | MEN1 (0.54) | MAPTRECQLRXFP1KMT2AMEN1 | |
| SCHEMBL5226165 | 0.81 | ATR (0.45) | PTK2KMT2AMEN1NAMPTHDAC1 | |
| SCHEMBL2880191 | 0.81 | LMNA (0.54) | RECQLRXFP1KMT2AMEN1NAMPT | |
| SCHEMBL12666625 | 0.79 | PTK2 (0.58) | PTK2KCNK3KCNK9MAPTRECQL | |
| SCHEMBL3662421 | 0.79 | F10 (0.53) | MAPTRECQLKMT2AMEN1F10 | |
| SCHEMBL1066788 | 0.79 | F10 (0.53) | MAPTRECQLRXFP1KMT2AMEN1 | |
| SCHEMBL12772560 | 0.79 | NPC1 (0.57) | MAPTKMT2AMEN1F10NAMPT | |
| SCHEMBL8350943 | 0.78 | NAMPT (0.49) | MAPTRECQLRXFP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403617-B1 | INCLUDING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, VARICELLA-ZOSTER VIRUS, HUMANHERPESVIRUSES-6 AND -7, AND KAPOSI HERPESVIRUS | AMERICAN HOME PRODUCTS CORP. | 2002-06-11 | — | — | US | disclosed |