Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 14/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 10/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7685567 | 1.00 | ADRB3 (0.43) | ADRB3ADRB2ADRB1RORCKDM4E | |
| SCHEMBL6074837 | 0.84 | ADRB3 (0.50) | ADRB3ADRB2 | |
| SCHEMBL7605286 | 0.84 | MEN1 (0.39) | ADRB3ADRB2ADRB1RORCKDM4E | |
| SCHEMBL7604462 | 0.82 | POLB (0.46) | RORCKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL7612169 | 0.79 | AR (0.44) | ADRB3MEN1KMT2A | |
| SCHEMBL7610085 | 0.79 | HDAC3 (0.44) | ADRB3KDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL7605273 | 0.77 | ADRB3 (0.44) | ADRB3ADRB2 | |
| SCHEMBL7656679 | 0.75 | ADRB3 (0.44) | ADRB3ADRB2 | |
| SCHEMBL2456888 | 0.75 | ADRB3 (0.53) | ADRB3ADRB2 | |
| SCHEMBL6074905 | 0.75 | ADRB3 (0.53) | ADRB3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |