Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 5/20 | 0.36 |
| ▸ | PDE4A | P27815 | 4/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683047 | 0.88 | PDE4A (0.38) | PDE4BPDE4APDE4CPDE4DTDP1 | |
| SCHEMBL6735881 | 0.88 | POLB (0.38) | PDE4BPDE4APDE4CPDE4DTDP1 | |
| SCHEMBL7683507 | 0.87 | PDE4B (0.38) | PDE4BPDE4APDE4CPDE4DTDP1 | |
| SCHEMBL7680208 | 0.84 | PDE4A (0.38) | PDE4BPDE4APDE4CPDE4DTDP1 | |
| SCHEMBL7677586 | 0.82 | HTT (0.41) | PDE4BPDE4APDE4CPDE4DL3MBTL1 | |
| SCHEMBL7676323 | 0.82 | PDE4A (0.39) | PDE4BPDE4APDE4CPDE4DTDP1 | |
| SCHEMBL7676322 | 0.81 | HTT (0.40) | PDE4BPDE4APDE4CPDE4DL3MBTL1 | |
| SCHEMBL7682613 | 0.81 | PDE4D (0.44) | PDE4BPDE4APDE4CPDE4DTDP1 | |
| SCHEMBL7679306 | 0.80 | ALDH1A1 (0.40) | TDP1L3MBTL1POLBTHRBRECQL | |
| SCHEMBL7680123 | 0.80 | THRB (0.38) | PDE4BPDE4APDE4CPDE4DTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472349-B1 | Pyridine-2,3-dicarboxylic acid diamides | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | claimed |