Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | HPGD | P15428 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 9/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29531707 | 0.75 | NPC1 (0.69) | ALDH1A1HPGDKDM4EMAPTUSP2 | |
| SCHEMBL824375 | 0.75 | NPC1 (0.69) | ALDH1A1HPGDKDM4EMAPTUSP2 | |
| SCHEMBL5324075 | 0.74 | NPC1 (0.50) | ALDH1A1HPGDKDM4EMAPTUSP2 | |
| SCHEMBL2493869 | 0.72 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4EMAPTUSP2 | |
| SCHEMBL29627559 | 0.72 | ALDH1A1 (0.65) | ALDH1A1HPGDKDM4EMAPTUSP2 | |
| SCHEMBL30096340 | 0.72 | ALDH1A1 (0.65) | ALDH1A1HPGDKDM4EMAPTUSP2 | |
| SCHEMBL30682 | 0.72 | ALDH1A1 (0.65) | ALDH1A1HPGDKDM4EMAPTUSP2 | |
| SCHEMBL3225774 | 0.71 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4EMAPTUSP2 | |
| SCHEMBL3132739 | 0.71 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4EMAPTUSP2 | |
| SCHEMBL3225779 | 0.71 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4EMAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482827-B1 | Matrix metalloproteinase inhibitors | PHARMACIA & UPJOHN S.P.A. (IT) | 2002-11-19 | — | — | US | disclosed |