Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576366 | 0.77 | SYK (0.61) | SYKCDC7ABCG2SLC2A1EGFR | |
| SCHEMBL6578695 | 0.74 | NOS1 (0.46) | SYKCDC7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7686057 | 0.73 | SYK (0.42) | SYKCDC7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11957643 | 0.70 | ABCC9 (0.50) | NPC1RAB9ASMN1; SMN2ABCG2CTSL | |
| SCHEMBL6580563 | 0.70 | ADORA2A (0.46) | — | |
| SCHEMBL6578904 | 0.67 | F10 (0.52) | — | |
| SCHEMBL6578699 | 0.66 | F2 (0.50) | SYKABCG2ALDH1A1 | |
| SCHEMBL7686054 | 0.64 | MAPT (0.37) | LRRK2CTSKALDH1A1MAPT | |
| SCHEMBL6576962 | 0.64 | F10 (0.64) | SYKCDC7ABCG2SLC2A1EGFR | |
| SCHEMBL7406589 | 0.64 | KMT2A (0.51) | NPC1RAB9ASMN1; SMN2CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6465459-B2 | INHIBIT THE ENZYME, FACTOR XA | BERLEX LABORATORIES, INC. | 2002-10-15 | — | — | US | disclosed |