Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686287 | 0.85 | CYP2D6 (0.38) | THRBALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL9031736 | 0.81 | USP2 (0.35) | ALDH1A1MAPTPOLBHRH3SMN1; SMN2 | |
| SCHEMBL7837763 | 0.79 | HRH2 (0.34) | THRBALDH1A1LMNAMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL7680696 | 0.77 | HRH2 (0.43) | THRBALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL7687002 | 0.76 | KDM4E (0.33) | ALDH1A1MAPTHRH3SMN1; SMN2CYP2D6 | |
| SCHEMBL7680139 | 0.75 | HRH2 (0.42) | ALDH1A1POLBNPC1HRH3SMN1; SMN2 | |
| SCHEMBL7684783 | 0.74 | ACHE (0.35) | ALDH1A1MAPTHRH3TP53SMN1; SMN2 | |
| SCHEMBL7837219 | 0.73 | HRH2 (0.40) | ALDH1A1POLBNPC1HRH3SMN1; SMN2 | |
| SCHEMBL9030284 | 0.72 | POLB (0.39) | ALDH1A1MAPTPOLBHRH3CYP2D6 | |
| Hydrochloric Acid SCHEMBL7680655 | 0.72 | POLB (0.38) | ALDH1A1MAPTPOLBHRH3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472397-B1 | Nitrogen-containing heterocyclic compounds having antiplatelet aggregation effect and medicinal use thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-10-29 | — | — | US | disclosed |