Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 9/20 | 0.33 |
| ▸ | HRH1 | P35367 | 9/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686287 | 0.91 | CYP2D6 (0.38) | KDM4EALDH1A1HRH3CYP2D6HRH2 | |
| SCHEMBL7684783 | 0.86 | ACHE (0.35) | KDM4EALDH1A1HRH3CYP2D6SMN1; SMN2 | |
| SCHEMBL7686904 | 0.85 | RAB9A (0.35) | KDM4EALDH1A1HRH3CYP2D6HRH2 | |
| SCHEMBL7687315 | 0.84 | HRH2 (0.36) | ALDH1A1HRH3CYP2D6HRH2HRH1 | |
| SCHEMBL7687003 | 0.82 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7677602 | 0.82 | HRH2 (0.36) | ALDH1A1HRH3CYP2D6HRH2HRH1 | |
| SCHEMBL9031736 | 0.78 | USP2 (0.35) | ALDH1A1HRH3CYP2D6SMN1; SMN2MAPT | |
| SCHEMBL7680139 | 0.78 | HRH2 (0.42) | ALDH1A1HRH3CYP2D6HRH2HRH1 | |
| SCHEMBL7680107 | 0.77 | GAA (0.38) | KDM4EALDH1A1HRH3CYP2D6HRH2 | |
| SCHEMBL7676237 | 0.77 | HRH3 (0.36) | KDM4EALDH1A1HRH3CYP2D6HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472397-B1 | Nitrogen-containing heterocyclic compounds having antiplatelet aggregation effect and medicinal use thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-10-29 | — | — | US | disclosed |
| EP-1070712-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS HAVING ANTIPLATELET AGGREGATION EFFECT AND MEDICINAL USE THEREOF | MEIJI SEIKA KAISHA LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |