Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 8/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6538833 | 0.90 | ADRB3 (0.61) | ADRB1ADRB3POLBALDH1A1MAPT | |
| SCHEMBL6478257 | 0.88 | POLB (0.50) | ADRB1ADRB3POLBALDH1A1GAA | |
| SCHEMBL6538633 | 0.87 | POLB (0.49) | ADRB1ADRB3POLBALDH1A1GAA | |
| SCHEMBL6538577 | 0.87 | POLB (0.49) | ADRB1ADRB3POLBALDH1A1GAA | |
| SCHEMBL6538563 | 0.86 | ADRB1 (0.54) | ADRB1ADRB3MEN1LMNAKMT2A | |
| SCHEMBL7040315 | 0.84 | POLB (0.49) | ADRB1ADRB3POLBALDH1A1GAA | |
| SCHEMBL6538732 | 0.84 | ADRB1 (0.50) | ADRB1ADRB3MEN1LMNAKMT2A | |
| SCHEMBL6539617 | 0.83 | ADRB1 (0.57) | ADRB1ADRB3POLBALDH1A1MAPT | |
| SCHEMBL7037437 | 0.83 | ALDH1A1 (0.52) | ADRB1ADRB3POLBALDH1A1GAA | |
| SCHEMBL7246502 | 0.83 | POLB (0.48) | ADRB1ADRB3POLBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |