SCHEMBL7686450

SCHEMBL7686450

NC(=O)C(O)c1nccs1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.38
NOS1 P29475 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ADAM17 P78536 1/20 0.38
CTSA P10619 8/20 0.37
FDPS P14324 3/20 0.34
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
RECQL P46063 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5585939 0.85 ALDH1A1 (0.43) ALDH1A1TSHRNOS1HSD17B10ADAM17
SCHEMBL15743831 0.80 ALDH1A1 (0.48) ALDH1A1ADAM17CTSAFDPSNPC1
SCHEMBL10591999 0.80 ALDH1A1 (0.39) ALDH1A1TSHRNOS1HSD17B10ADAM17
SCHEMBL14796485 0.80 ALDH1A1 (0.39) ALDH1A1TSHRNOS1HSD17B10ADAM17
SCHEMBL29120809 0.78 ALDH1A1 (0.38) ALDH1A1TSHRNOS1HSD17B10ADAM17
SCHEMBL27835941 0.78 ALDH1A1 (0.38) ALDH1A1TSHRNOS1HSD17B10ADAM17
SCHEMBL30439698 0.78 ALDH1A1 (0.38) ALDH1A1TSHRNOS1HSD17B10ADAM17
SCHEMBL1007892 0.78 ALDH1A1 (0.42) ALDH1A1TSHRNOS1HSD17B10CTSA
SCHEMBL14665101 0.76 ALDH1A1 (0.40) ALDH1A1ADAM17CTSASMN1; SMN2L3MBTL1
SCHEMBL14664051 0.76 ALDH1A1 (0.40) ALDH1A1ADAM17CTSANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6339042-B1 FOR COMBATING UNDESIRED PLANT GROWTH AMERICAN CYANAMID CO. 2002-01-15 US disclosed
EP-1047679-A1 HERBICIDAL N-ALKENYL HETEROARYLYLOXYACETAMIDES AMERICAN CYANAMID COMPANY (US) 2000-11-02 EP disclosed
WO-1999025702-A1 HERBICIDAL N-ALKENYL HETEROARYLYLOXYACETAMIDES AMERICAN CYANAMID COMPANY (US) 1999-05-27 WO disclosed
EP-0192148-B1 2,4-DICHLOROTHIAZOLE DERIVATIVES AND PROCESS FOR THEIR PREPARATION BAYER AG (DE) 1989-01-18 EP disclosed
US-4788208-A FUNGICIDES; INTERMEDIATES FOR HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1988-11-29 US disclosed
EP-0195237-B1 4,5-SUBSTITUTED-1,3-THIAZOL-2-YLOXYACETAMIDE BAYER AG (DE) 1988-11-02 EP disclosed
EP-0195237-A1 4,5-Substituted-1,3-thiazol-2-yloxyacetamide BAYER AG (DE) 1986-09-24 EP disclosed
EP-0192148-A1 2,4-Dichlorothiazole derivatives and process for their preparation BAYER AG (DE) 1986-08-27 EP disclosed