Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CTSA | P10619 | 7/20 | 0.40 |
| ▸ | FDPS | P14324 | 3/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10591999 | 0.85 | ALDH1A1 (0.39) | ALDH1A1TSHRNOS1HSD17B10CTSA | |
| SCHEMBL7686450 | 0.85 | ALDH1A1 (0.39) | ALDH1A1TSHRNOS1HSD17B10CTSA | |
| SCHEMBL14796485 | 0.85 | ALDH1A1 (0.39) | ALDH1A1TSHRNOS1HSD17B10CTSA | |
| SCHEMBL27835941 | 0.84 | ALDH1A1 (0.38) | ALDH1A1TSHRNOS1HSD17B10CTSA | |
| SCHEMBL1007892 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TSHRNOS1HSD17B10CTSA | |
| SCHEMBL30439698 | 0.84 | ALDH1A1 (0.38) | ALDH1A1TSHRNOS1HSD17B10CTSA | |
| SCHEMBL29120809 | 0.84 | ALDH1A1 (0.38) | ALDH1A1TSHRNOS1HSD17B10CTSA | |
| SCHEMBL6252040 | 0.79 | CTSA (0.40) | ALDH1A1CTSAADAM17 | |
| SCHEMBL30595113 | 0.79 | CTSA (0.40) | ALDH1A1CTSAADAM17 | |
| SCHEMBL30218944 | 0.79 | ALDH1A1 (0.43) | ALDH1A1CTSAADAM17SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070004675-A1 | Inhibitors of VEGF receptor and HGF receptor signaling | METHYLGENE, INC. | 2007-01-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004675-A1 | Inhibitors of VEGF receptor and HGF receptor signaling | HGF, MET, FLT1 | ALDH1A1 1649/4885TSHR 396/4885NOS1 3159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.