Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 15/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686951 | 0.97 | CASP1 (0.46) | CASP1CASP3 | |
| SCHEMBL7680016 | 0.95 | CASP1 (0.48) | CASP1CASP3 | |
| SCHEMBL7683677 | 0.91 | CASP1 (0.50) | CASP1CASP3 | |
| SCHEMBL7683292 | 0.90 | CASP1 (0.58) | CASP1CASP3 | |
| SCHEMBL7678093 | 0.89 | CASP1 (0.42) | CASP1CASP3 | |
| SCHEMBL8171644 | 0.87 | CASP1 (0.41) | CASP1CASP3SMN1; SMN2 | |
| SCHEMBL8178640 | 0.86 | CASP1 (0.40) | CASP1CASP3SMN1; SMN2 | |
| SCHEMBL7678223 | 0.86 | CASP1 (0.54) | CASP1CASP3 | |
| SCHEMBL7675664 | 0.86 | CASP1 (0.41) | CASP1CASP3NPC1RECQLRAB9A | |
| Hydrochloric Acid SCHEMBL7690065 | 0.86 | CASP1 (0.40) | CASP1CASP3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136834-A | TETRAZOLE PEPTIDES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | claimed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | claimed |
| US-6376484-B1 | FOR PREVENTION AND/OR TREATMENT OF VARIOUS KINDS OF INFLAMMATORY DISEASE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-04-23 | — | — | US | disclosed |
| US-6136834-A | TETRAZOLE PEPTIDES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | disclosed |