Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686564 | 0.87 | LPAR1 (0.43) | ADRB1ADRB3ALDH1A1POLBMAPT | |
| SCHEMBL7692498 | 0.87 | LPAR1 (0.39) | GAAALDH1A1PDGFRAKDRMEN1 | |
| SCHEMBL6487652 | 0.87 | ALDH1A1 (0.43) | ADRB1ADRB3ALDH1A1KDRMEN1 | |
| SCHEMBL6488702 | 0.86 | LPAR1 (0.39) | GAAALDH1A1KDRMEN1KMT2A | |
| SCHEMBL7689867 | 0.85 | PDGFRA (0.36) | ADRB1ADRB3ALDH1A1PDGFRAKDR | |
| SCHEMBL7689864 | 0.85 | PDGFRA (0.36) | ADRB1ADRB3ALDH1A1PDGFRAKDR | |
| SCHEMBL7692913 | 0.84 | LPAR1 (0.39) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL7692473 | 0.84 | MET (0.38) | ALDH1A1PDGFRAKDRMEN1KMT2A | |
| SCHEMBL6539970 | 0.84 | GAA (0.51) | ADRB1ADRB3GAAALDH1A1MEN1 | |
| SCHEMBL6478360 | 0.83 | MAPT (0.39) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |