Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 4/20 | 0.46 |
| ▸ | CTSL | P07711 | 4/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 6/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7039596 | 0.93 | CTSV (0.43) | CTSVCTSLPDCD1CD274MEN1 | |
| SCHEMBL6479313 | 0.92 | CTSV (0.40) | CTSVCTSLPDCD1CD274POLB | |
| SCHEMBL6479308 | 0.92 | CTSV (0.40) | CTSVCTSLPDCD1CD274POLB | |
| SCHEMBL7039802 | 0.91 | MEN1 (0.41) | CTSVCTSLPDCD1CD274MEN1 | |
| SCHEMBL7036429 | 0.89 | KMT2A (0.41) | CTSVCTSLPDCD1CD274MEN1 | |
| SCHEMBL6541035 | 0.89 | POLB (0.44) | CTSVCTSLPDCD1CD274KMT2A | |
| SCHEMBL6541029 | 0.89 | POLB (0.44) | CTSVCTSLPDCD1CD274KMT2A | |
| SCHEMBL7036432 | 0.89 | KMT2A (0.41) | CTSVCTSLPDCD1CD274MEN1 | |
| SCHEMBL7042818 | 0.88 | FFAR1 (0.44) | CTSVCTSLPDCD1CD274MAPT | |
| SCHEMBL7686556 | 0.85 | OPRD1 (0.37) | MAPTPOLBBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |