Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7687506 | 0.91 | IDO1 (0.38) | IDO1PLAUPSEN1PSEN2APH1B | |
| SCHEMBL7089075 | 0.76 | PSEN1 (0.36) | PLAUPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28038452 | 0.72 | CHRM2 (0.40) | TSHR | |
| SCHEMBL6875865 | 0.70 | IDO1 (0.39) | IDO1TSHRPLAUPSEN1PSEN2 | |
| SCHEMBL6875859 | 0.70 | IDO1 (0.39) | IDO1TSHRPLAUPSEN1PSEN2 | |
| SCHEMBL14990041 | 0.69 | PLAU (0.44) | IDO1TSHRPLAUPSEN1PSEN2 | |
| SCHEMBL14760073 | 0.69 | PLAU (0.44) | IDO1TSHRPLAUPSEN1PSEN2 | |
| SCHEMBL29949831 | 0.69 | PLAU (0.44) | IDO1TSHRPLAUPSEN1PSEN2 | |
| SCHEMBL11319810 | 0.68 | HTR2A (0.40) | — | |
| SCHEMBL7685203 | 0.68 | L3MBTL1 (0.38) | IDO1PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362141-B1 | ORGANOLEPTIC; PERFUMES, COSMETICS, CLEANING COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-03-26 | — | — | US | claimed |
| US-6342612-B1 | FRAGRANCES | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-01-29 | — | — | US | claimed |