Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174527 | 0.94 | HTT (0.46) | HTTKMT2ASMN1; SMN2CMA1ALDH1A1 | |
| SCHEMBL8723261 | 0.87 | ACACB (0.41) | HTTKMT2ASMN1; SMN2CMA1ALDH1A1 | |
| SCHEMBL7686964 | 0.87 | HTT (0.39) | HTTKMT2ASMN1; SMN2CMA1ALDH1A1 | |
| SCHEMBL7687627 | 0.82 | HTT (0.39) | HTTKMT2ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL9232299 | 0.81 | HTT (0.54) | HTTCMA1TDP1GPR119TNF | |
| SCHEMBL8718743 | 0.80 | USP2 (0.46) | HTTKMT2ASMN1; SMN2CMA1TDP1 | |
| SCHEMBL8721370 | 0.79 | HTT (0.48) | HTTKMT2ACMA1TDP1GPR119 | |
| SCHEMBL7687404 | 0.78 | CFTR (0.47) | HTTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8105481 | 0.77 | HTT (0.39) | HTTKMT2ASMN1; SMN2CMA1ALDH1A1 | |
| SCHEMBL8718390 | 0.76 | HTT (0.50) | HTTSMN1; SMN2CMA1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362206-B1 | FUNGICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-26 | — | — | US | disclosed |
| US-6034248-A | FUNGICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-03-07 | — | — | US | disclosed |
| EP-0809640-A1 | AZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025410-A1 | AZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-22 | — | — | WO | disclosed |