Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 19/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7681433 | 0.92 | MEN1 (0.51) | MEN1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL7677377 | 0.80 | PRKCZ (0.46) | MEN1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL5503933 | 0.80 | MAPT (0.70) | MEN1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL6992785 | 0.79 | MAPT (0.63) | MEN1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL5712810 | 0.79 | MAPT (0.65) | MEN1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL7682075 | 0.79 | MEN1 (0.52) | MEN1MAPTKMT2A | |
| SCHEMBL5712873 | 0.78 | MEN1 (0.64) | MEN1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL7001600 | 0.78 | ADORA1 (0.67) | MEN1GAAMAPTKMT2A | |
| SCHEMBL5506679 | 0.78 | KMT2A (0.64) | MEN1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL7684068 | 0.78 | MAPT (0.53) | MEN1ALDH1A1GAAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403606-B1 | ANTIINFLAMMATORY, ANTIARTHRITIS, A DRUG FOR INHIBITING BONE RESORPTION, IMMUNOSUPPRESSANT | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 2002-06-11 | — | — | US | disclosed |
| US-6046189-A | ANTI-INFLAMMATORY DRUG, PARTICULARLY, A DRUG FOR PREVENTING OR TREATING ARTHRITIS, A DRUG FOR INHIBITING BONE RESORPTION, IMMUNOSUPPRESSANT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-04-04 | — | — | US | disclosed |
| EP-0900223-A1 | THIENOPYRIDINE DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997040050-A1 | THIENOPYRIDINE DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |